| Description | TriacetonaMine (Vincubine) protects the activitis of superoxide dismutase(SOD) and creatine phos-phate kinase (CPK); it also inhibits CaCl2 induced agglomeration of thromocyte. Triacetonamine can improve the constructile function of heart mus-cles of acute anemia and decrease the content of malodialdehyde (MDA) in the heart muscles. |
| In vivo | Triacetonamine(TAA)能够改善急性贫血时心肌的收缩功能,并降低心肌中丙二醛(MDA)的含量。TAA保护超氧化物歧化酶(SOD)和肌酸磷酸激酶(CPK)的活性,同时抑制由CaCl2引起的血小板聚集。 |
| Synonyms | 四甲基哌啶酮, Odoratine, tempidon, tmpone, Vincubine, 2,2,6,6-Tetramethyl-4-piperidinone |
| molecular weight | 155.24 |
| Molecular formula | C9H17NO |
| CAS | 826-36-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 55 mg/mL (354.29 mM), Sonication is recommended. |
| References | 1. Protective Effects of Triacetonamine on Acute Ischemia Isolated Rat Heart Muscles[J]. Supplement to the Journal of Sun Yatsen University, 1994. |