| Description | trans-isrib A17 (ISR-IN-1) is an potent inhibitor of the integrated stress response with EC50 of 0.6 nM. |
| Synonyms | ISR-IN-1 |
| molecular weight | 487.32 |
| Molecular formula | C22H22Cl2F2N2O4 |
| CAS | 1628478-15-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: Slightly soluble |
| References | 1. Hearn BR, et al. Structure-Activity Studies of Bis-O-Arylglycolamides: Inhibitors of the Integrated Stress Response. ChemMedChem. 2016 Apr 19;11(8):870-80. |