| Description | TPh A (Triphenyl Compound A) is an inhibitor of the nuclear protein pirin (Ki: 0.6 uM), a protein that can be used as a bioprobe to regulate pirin-related functions. |
| In vitro | 在 MCF7、MDA-MB231、HeLa、DU145、HepG2、A549、HT1080、WM266-4和 SK-MEL-28 细胞中，TPh A（0-100 μM；48小时）未表现出对多种人类癌细胞系具有强效细胞毒活性[1]。 |
| Synonyms | Triphenyl Compound A |
| molecular weight | 399.53 |
| Molecular formula | C21H21NO3S2 |
| CAS | 21306-65-0 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 100 mg/mL (250.29 mM), Sonication is recommended. |
| References | 1. Isao Miyazaki, et al. A Small-Molecule Inhibitor Shows That Pirin Regulates Migration of Melanoma Cells. Nat Chem Biol. 2010 Sep;6(9):667-73. |