| Description | TPC-144 is a potent and selective LSD1 inhibitor with a reversible inhibition mechanism. TPC-144 has antitumor activity in several human AML and SCLC cell lines and xenograft models. |
| Synonyms | TPC144, TPC 144 |
| molecular weight | 515.59 |
| Molecular formula | C31H31F2N3O2 |
| CAS | 2098621-17-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. TPC-144, a novel reversible LSD1 inhibitor, exhibited strong antitumor activity in preclinical models of AML and SCLC A. Kawagishi, et al. European Journal of Cancer, December 2016Volume 69, Supplement 1, Pages S86–S87. doi: http://dx.doi.org/10.1016/S0959-8049(16)32853-2 |