| Description | TP-16 is a novel potent and selective EP4 antagonist that blocks the function of IMCs and enhances cytotoxic T cell-mediated tumor elimination in vivo. |
| Target activity | EP4:2.1 nM |
| molecular weight | 439.5 |
| Molecular formula | C24H22FNO4S |
| CAS | 2332972-26-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Lu W, et al. Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer. EMBO Mol Med. 2021 Jan 11;13(1):e12798. |