| Description | TP-1454 is an activator against PKM2 with a biochemically determined AC50 of 10 Nm. It can regulate tumor immune responses by acting on T regulatory cells. |
| molecular weight | 462.46 |
| Molecular formula | C19H22F4N4O3S |
| CAS | 2490276-04-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Weagel EG, et al. Med Chem Res 31, 1068–1087 (2022). 2. Sommakia S, et al. Sumitomo Pharma Oncology, Inc., Lehi, UT |