| Description | Topoisomerase II inhibitor 6 (Compound 5) is a tryptanthrin derivative. Topoisomerase II inhibitor 6 is a potent and selective topoisomerase II inhibitor. Topoisomerase II inhibitor 6 blocks the CCRF-CEM cell cycle in the G2 phase and induces DNA double-strand breaks (DSB). Topoisomerase II inhibitor 6 exhibits antiproliferative activity on different tumor cell lines. Topoisomerase II inhibitor 6 has the potential for the research of cancer diseases [1]. |
| molecular weight | 334.37 |
| Molecular formula | C19H18N4O2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |