| Description | Topilutamide (Fluridil) is a topical nonsteroidal antiandrogen. |
| In vivo | 治疗转移性前列腺癌常用的方法之一是通过包括Flutamide、Nilutamide、Bicalutamide和Topilutamide在内的第一代非甾体抗雄激素(NSAAs)进行治疗[1]。 |
| Synonyms | Fluridil, BP766 |
| molecular weight | 403.23 |
| Molecular formula | C13H11F6N3O5 |
| CAS | 260980-89-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 125 mg/mL (310.00 mM), Sonication is recommended. |
| References | 1. Suresh PS, et al. Review of HPLC and LC-MS/MS assays for the determination of various nonsteroidal anti-androgens used in the treatment of prostate cancer. Biomed Chromatogr. 2017 Jun 21. |