| Description | Tocofersolan (TPGS) is a polyethylene glycol derivative of α-tocopherol and synthetic water-soluble version of Tocopherol. Tocofersolan is an oral treatment of vitamin E deficiency due to digestive malabsorption in pediatric patients with congenital chronic cholestasis or hereditary chronic cholestasis. |
| Synonyms | Vitamin E-TPGS, Tocophersolan, TPGS, D-α-Tocopherol polyethylene glycol 1000 succinate, 托可索仑, 维生素E聚乙二醇琥珀酸酯 |
| molecular weight | N/A |
| CAS | 9002-96-4 |
| Storage | store at low temperature,keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 31.25 mg/mL (54.36 mM), Sonication is recommended. |
| References | 1. Thébaut, A, Nemeth A , Le Mouhaër, J, et al. Oral Tocofersolan Corrects or Prevents Vitamin E Deficiency in Children With Chronic Cholestasis[J]. Journal of Pediatric Gastroenterology & Nutrition, 2016, 63(6):1. 2. Roongpraiwan R , Suthutvoravut U , Feungpean B , et al. Effect of oral vitamin E supplementation in children with cholestasis.[J]. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2002, 85 Suppl 4:S1199. 3. Rehim WM, et al. Antioxidant capacity in Fasciola hepatica patients before and after treatment with triclabendazole alone or in combination with ascorbic acid (vitamin C) and tocofersolan (vitamin E). Arzneimittelforschung. 2003;53(3):214-20. |