| Description | TNF-α-IN-8 (compound I-42) is an isoindole-imide-based inhibitor of tumor necrosis factor-alpha (TNF-α) with applications in researching various diseases including cancer, heart disease, osteoporosis, and autoimmune disorders. Additionally, this compound serves as a click chemistry reagent, possessing an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) or strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Alkyne, DBCO, or BCN groups. |
| molecular weight | 356.29 |
| Molecular formula | C15H12N6O5 |
| CAS | 444287-85-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |