| Description | TMDJ-035 is a selective inhibitor of the RyR2 (ryanodine receptor 2). It effectively suppresses abnormal calcium (Ca^2+) waves and transients in isolated cardiomyocytes derived from mice with RyR2 mutations. As such, TMDJ-035 serves as a valuable tool in research for elucidating the gating mechanisms and dynamics of the RyR2 channel [1]. |
| molecular weight | 347.29 |
| Molecular formula | C16H12F3N5O |
| CAS | 2681302-83-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |