| Description | TMA-DPH is a hydrophobic fluorescent membrane probe (Ex: 355 nm; Em: 430 nm). |
| In vitro | TMA-DPH荧光寿命在低于2μM的同一临界浓度下保持恒定值6.2±0.2 ns，但在更高浓度时显著降低；然而，该降低速度在5μM以上会放缓。TMA-DPH荧光各向异性的变化趋势与荧光寿命相似，起初在2μM以下保持恒定值0.283±0.003，随后在5μM时迅速降至0.270±0.003，并在更高浓度下继续以较慢速度下降[2]。 |
| molecular weight | 461.62 |
| Molecular formula | C28H31NO3S |
| CAS | 115534-33-3 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 55 mg/ml (119.15 mM) |
| References | 1. Illinger D, et al. The kinetic aspects of intracellular fluorescence labeling with TMA-DPH support the maturation model for endocytosis in L929 cells. J Cell Biol. 1994 May;125(4):783-94. 2. Illinger D, et al. A comparison of the fluorescence properties of TMA-DPH as a probe for plasma membrane and for endocytic membrane. Biochim Biophys Acta. 1995 Oct 4;1239(1):58-66. |
| Citations | 1. Zhao X, Lian X, Xie J, et al.Accumulated cholesterol protects tumours from elevated lipid peroxidation in the microenvironment.Redox Biology.2023: 102678. |