| Description | Tipifarnib S enantiomer ((S)-(-)-R-115777) is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase inhibitor (IC50: 0.6 nM). |
| Synonyms | Tipifarnib S enantiomer, (S)-(-)-R-115777, (S)-Tipifarnib, IND-58359 S enantiomer |
| molecular weight | 489.4 |
| Molecular formula | C27H22Cl2N4O |
| CAS | 192185-71-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 25 mg/mL (51.08 mM), Sonication is recommended. |
| References | 1. Kraus JM, et al. Rational modification of a candidate cancer drug for use against Chagas disease. J Med Chem. 2009 Mar 26;52(6):1639-47. |