Description | Timosaponin BII (Prototimosaponin A III) has anti-dementia activity and may be useful for the treatment of type 2 diabetes. Timosaponin BII has antioxidant activity, can inhibit the up-regulation of BACE1 and reduced the over-production of β-CTF and Aβ in rat retina, which was induced by FeCl . |
Synonyms | 知母皂苷BII, Prototimosaponin A III |
molecular weight | 921.07 |
Molecular formula | C45H76O19 |
CAS | 136656-07-0 |
Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 50 mg/mL (54.34 mM) |
References | 1. Huang JF, et al. BMC Complement Altern Med. 2012 Oct 22;12:189. 2. Zhou WB, et al. J Asian Nat Prod Res. 2010 Nov;12(11):955-61. 3. Tang YH, et al. Planta Med. 2012 Jan;78(1):18-23. |