| Description | TIE-2/VEGFR-2 kinase-IN-4, a benzimidazole derivative, serves as a potent inhibitor of the tyrosine kinase receptors TIE-2 and VEGFR-2, exhibiting inhibitory concentration (IC50) values of 5.2 nM and 5.1 nM, respectively. This compound is utilized in angiogenesis research [1]. |
| Target activity | VEGFR2:5.1 nM, Tie2:5.2 mM |
| molecular weight | 539.44 |
| Molecular formula | C26H17F4N5O4 |
| CAS | 433224-29-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |