| Description | Thioacetanilide (NSC-36984) possesses potential anti-inflammatory and analgesic activities. |
| Synonyms | NSC 36984, NSC36984, 硫代乙酰苯胺, NSC-36984 |
| molecular weight | 151.23 |
| Molecular formula | C8H9NS |
| CAS | 637-53-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 55 mg/ml (363.68 mM) |
| References | 1. Lu X, et al. Arylazolyl(azinyl)thioacetanilides. Part 20: Discovery of novel purinylthioacetanilides derivatives as potent HIV-1 NNRTIs via a structure-based bioisosterism approach. Bioorg Med Chem. 2016 Sep 15;24(18):4424-4433. 2. Li X, et al. Arylazolyl(azinyl)thioacetanilides: Part 19: Discovery of Novel Substituted Imidazo[4,5-b]pyridin-2-ylthioacetanilides as Potent HIV NNRTIs Via a Structure-based Bioisosterism Approach. Chem Biol Drug Des. 2016 Aug;88(2):241-53. 3. Wan ZY, et al. Pyrimidine sulfonylacetanilides with improved potency against key mutant viruses of HIV-1 by specific targeting of a highly conserved residue. Eur J Med Chem. 2015 Sep 18;102:215-22. 4. Li W, et al. Discovery of potent HIV-1 non-nucleoside reverse transcriptase inhibitors from arylthioacetanilide structural motif. Eur J Med Chem. 2015 Sep 18;102:167-79. |