| Description | Thioacetamide is a hepatotoxicant used widely to induce experimental liver lesions, develops hepatocellular necrosis and subsequent inflammation (mainly M1-/M2-macrophages without neutrophil infiltration) in rats. |
| Synonyms | TAA, 硫代乙酰胺 |
| molecular weight | 75.13 |
| Molecular formula | C2H5NS |
| CAS | 62-55-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 55 mg/mL (732.06 mM) H2O: 16.3 g/100 mL (25 oC), Sonication and heating to 60℃ are recommended. |
| References | 1. Staňková P, et al. The toxic effect of thioacetamide on rat liver in vitro. Toxicol In Vitro. 2010 Dec;24(8):2097-103. 2. Kuramochi M, et al. Involvement of neutrophils in rat livers by low-dose thioacetamide administration. J Vet Med Sci. 2021 Mar 11;83(3):390-396. |