| Description | Thio-NAD, a thione-modified derivative of the signaling molecule and enzyme cofactor NAD+, can substitute for NAD+ as a cofactor in alkaline phosphatase (ALP) enzyme activity assays. It is utilized as a substrate in dual-enzyme cycling ELISA for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein, or surface glycoprotein, and live M. tuberculosis in patient sputum. Thio-NAD is characterized by its absorbance at 405 nm, distinguishing it from other cofactors. |
| Synonyms | Thionicotinamide NAD, Thionicotinamide adenine dinucleotide |
| molecular weight | 679.49 |
| Molecular formula | C21H27N7O13P2S |
| CAS | 4090-29-3 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | PBS pH 7.2: 10 mg/ml |