| Description | Thalidomide-O-PEG2-propargyl (E3 Ligase Ligand-Linker Conjugates 32) is a chemical compound that has been synthesized as a conjugate of an E3 ligase ligand and a linker. It incorporates the cereblon ligand based on Thalidomide, along with a 2-unit PEG linker. This compound is specifically designed for use in PROTAC technology, which utilizes ligand-induced protein degradation [1]. |
| Synonyms | E3 ligase Ligand-Linker Conjugates 32 |
| molecular weight | 400.38 |
| Molecular formula | C20H20N2O7 |
| CAS | 2098487-52-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461. |
Thalidomide-O-PEG2-propargyl
CAS No.: 2098487-52-4
Thalidomide-O-PEG2-propargyl (E3 Ligase Ligand-Linker Conjugates 32) is a chemical compound that has been synthesized as
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.