| Description | Thalidomide-5-propoxyethanamine acts as a cereblon (CRBN) ligand derived from Thalidomide, and it serves the purpose of recruiting the CRBN protein. |
| In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| molecular weight | 359.38 |
| Molecular formula | C18H21N3O5 |
| CAS | 2357107-60-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Mainolfi, Nello, et al. IRAK DEGRADERS AND USES THEREOF. Patent US20190192668A1. |
Thalidomide-5-propoxyethanamine
CAS No.: 2357107-60-7
Thalidomide-5-propoxyethanamine acts as a cereblon (CRBN) ligand derived from Thalidomide, and it serves the purpose of
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