| Description | Tezepelumab (AMG 157) is a humanized monoclonal antibody (IgG2λ) targeting TSLP that prevents TSLP from interacting with its heterodimer receptor. Tezepelumab can be used to study advanced asthma disease. |
| In vitro | Tezepelumab阻断胸腺基质淋巴生成素，这是一种上皮细胞衍生的细胞因子，与哮喘的发病机制有关[1]。 |
| Synonyms | Tezepelumab-ekko, MEDI 19929, AMG 157 |
| molecular weight | N/A |
| CAS | 1572943-04-4 |
| Storage | store at low temperature | store at -20°C |
| References | 1. Menzies-Gow A, et, al. Tezepelumab in Adults and Adolescents with Severe, Uncontrolled Asthma. N Engl J Med. 2021 May 13;384(19):1800-1809. |