| Description | Terbufibrol reduces the levels of serum total cholesterol in normal and hypercholesterolemic male rats. |
| In vivo | Terbufibrol（20-200 mg/kg）在所有三种饮食（胆固醇、高蛋白、高脂肪）的动物体内降低血清TC，胆固醇降低的程度分别为154%、80%和70%。Terbufibrol能够降低采用高蛋白脂肪饮食（HPF-diet）的动物体内的HDL、HDL-TC、LDL、LDL-TC以及LDL-TC/PL水平。此外，Terbufibrol按剂量依赖方式降低LDL-TC。Clofibrate（200 mg/kg）降低HDL和HDL-TC，同时增加LDL[1]。 |
| molecular weight | 344.4 |
| Molecular formula | C20H24O5 |
| CAS | 56488-59-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 3.44 mg/mL (10 mM), Sonication is recommended. |
| References | 1. Howard AN, et al. The hypocholesterolemic effect of terbufibrol and other drugs in normal and hypercholesterolemic baboons. Atherosclerosis. 1979 Apr;32(4):367-80. |