| Description | Tenofovir-C3-O-C15-CF3 (ammonium) demonstrates prolonged half-life values compared to tenofovir in human liver microsomes. It exhibits potent anti-HIV activity in vitro and enhances pharmacokinetic properties in vivo. |
| Synonyms | Tenofovir-C3-O-C15-CF3 ammonium |
| molecular weight | 640.73 |
| Molecular formula | C28H52F3N6O5P |
| CAS | 2611373-80-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Pribut N, et al. ω-Functionalized Lipid Prodrugs of HIV NtRTI Tenofovir with Enhanced Pharmacokinetic Properties. J Med Chem. 2021 Sep 9;64(17):12917-12937. |
Tenofovir-C3-O-C15-CF3 ammonium
CAS No.: 2611373-80-7
Tenofovir-C3-O-C15-CF3 (ammonium) demonstrates prolonged half-life values compared to tenofovir in human liver microsome
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