| Description | Temozolomide Acid (TMZA) is a metabolite of temozolomide (TMZ). Temozolomide processes anticancer activity in vitro. Temozolomide (TMZ) is an oral alkylating agent used to treat glioblastoma multiforme (GBM) and astrocytomas. |
| Synonyms | TMZA, 3,4-二氢-3-甲基-4-氧代咪唑并[5,1-D]-1,2,3,5-四嗪-8-甲酰胺酸 |
| molecular weight | 195.14 |
| Molecular formula | C6H5N5O3 |
| CAS | 113942-30-6 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | H2O: Insoluble DMSO: 65 mg/ml (333.09 mM) |
| References | 1. Lee S Y . Temozolomide resistance in glioblastoma multiforme[J]. Genes & Diseases, 2016, 3( 3):198-210. 2. Karachi A , Dastmalchi F , Mitchell D A , et al. Temozolomide for Immunomodulation in the Treatment of Glioblastoma[J]. Neuro Oncology, 2018, 20(12):1566-1572. |