| Description | Teloxantrone, a DNA topoisomerase II inhibitor, is used potentially for the treatment of solid tumors. |
| Synonyms | PD-113309, Moxantrazole, NSC-355644, CI-937, DuP-937, Teloxantrone |
| molecular weight | 465.94 |
| Molecular formula | C21H28ClN5O5 |
| CAS | 132937-88-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Armand JP. New anticancer drugs in Europe. Gan To Kagaku Ryoho. 1997 May;24 Suppl 1:70-93. Review. PubMed PMID: 9210890. 2. Gogas H, Mansi JL. New drugs. The anthrapyrazoles. Cancer Treat Rev. 1996 Nov;21(6):541-52. Review. PubMed PMID: 8599804. 3. Renner U, Blanz J, Freund S, Waidelich D, Ehninger G, Zeller KP. Biotransformation of CI-937 in primary cultures of rat hepatocytes. Formation of glutathione conjugates. Drug Metab Dispos. 1995 Jan;23(1):94-101. PubMed PMID: 7720531. 4. Raghavan K, Nemeth G, Gray D, Hussain MA. Stabilization of an anthrapyrazole antitumour agent, DuP 937, on complexation with heptakis(2,6-di-O-methyl)-beta-cyclodextrin in aqueous solution. J Pharm Biomed Anal. 1994 Oct;12(10):1259-64. PubMed PMID: 7841220. |