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Taurocholic Acid 3-sulfate (sodium salt)

CAS No.: 71781-33-4

Taurocholic acid 3-sulfate (TCA3S) is a metabolite of the conjugated bile acid taurocholic acid .1Plasma levels of TCA3S
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Description Taurocholic acid 3-sulfate (TCA3S) is a metabolite of the conjugated bile acid taurocholic acid .1Plasma levels of TCA3S are elevated in wild-type andSortilin 1(Sort1) knockout mice at 6 hours following bile duct ligation (BDL) and are further elevated inSort1knockout mice at 24 hours post-BDL.2
molecular weight 641.74
Molecular formula C26H45NNa2O10S2
CAS 71781-33-4
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility PBS (pH 7.2): 1 mg/mL DMSO: 0.3 mg/mL DMF: 1 mg/mL
References 1. Lefebvre, P., Cariou, B., Lien, F., et al.Role of bile acids and bile acid receptors in metabolic regulationPhysiol. Rev.89(1)147-191(2009) 2. Li, J., Woolbright, B.L., Zhao, W., et al.Sortilin 1 loss-of-function protects against cholestatic liver injury by attenuating hepatic bile acid accumulation in bile duct ligated miceToxicol. Sci.161(1)34-47(2018)