PeptideDB

TAN67

CAS No.: 1217628-73-3

TAN67 is the first effective selective non-peptide delta1 opioid receptor.
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Description TAN67 is the first effective selective non-peptide delta1 opioid receptor.
Synonyms SB-205607 dihydrobromide, SB 205607 dihydrobromide, SB205607 dihydrobromide, TAN-67, TAN 67
molecular weight 506.282
Molecular formula C23H26Br2N2O
CAS 1217628-73-3
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. Burford NT, Livingston KE, Canals M, Ryan MR, Budenholzer LM, Han Y, Shang Y, Herbst JJ, O'Connell J, Banks M, Zhang L, Filizola M, Bassoni DL, Wehrman TS, Christopoulos A, Traynor JR, Gerritz SW, Alt A. Discovery, synthesis, and molecular pharmacology of selective positive allosteric modulators of the δ-opioid receptor. J Med Chem. 2015 May 28;58(10):4220-9. doi: 10.1021/acs.jmedchem.5b00007. Epub 2015 May 7. PubMed PMID: 25901762; PubMed Central PMCID: PMC4703104. 2. Martin NA, Prather PL. Interaction of co-expressed mu- and delta-opioid receptors in transfected rat pituitary GH(3) cells. Mol Pharmacol. 2001 Apr;59(4):774-83. PubMed PMID: 11259622. 3. Ohsawa M, Nagase H, Kamei J. Role of intracellular calcium in modification of mu and delta opioid receptor-mediated antinociception by diabetes in mice. J Pharmacol Exp Ther. 1998 Aug;286(2):780-7. PubMed PMID: 9694934. 4. Quock RM, Hosohata Y, Knapp RJ, Burkey TH, Hosohata K, Zhang X, Rice KC, Nagase H, Hruby VJ, Porreca F, Roeske WR, Yamamura HI. Relative efficacies of delta-opioid receptor agonists at the cloned human delta-opioid receptor. Eur J Pharmacol. 1997 May 12;326(1):101-4. PubMed PMID: 9178661.