| Description | Tafenoquine Succinate (WR 238605 (Succinate)) is an 8-aminoquinoline. and is an agent of anti-malarial prophylactic. |
| In vivo | 当在其ED100（6 mg/kg）的两倍剂量下测试时，Tafenoquine的抗疟活性在人源化/CYP 2D6基因敲入小鼠中部分恢复[1]。 |
| Synonyms | 他非诺喹琥珀酸盐, WR 238605 (Succinate) |
| molecular weight | 581.58 |
| Molecular formula | C28H34F3N3O7 |
| CAS | 106635-81-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 120 mg/mL (206.33 mM), Sonication is recommended. |
| References | 1. Marcsisin SR, et al. Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds. Malar J. 2014 Jan 3;13:2. |