| Description | TA-993 is a calcium channel antagonist. TA-993 has an antithrombotic effect. |
| Synonyms | TA 993, TA993, TA-993 |
| molecular weight | 528.62 |
| Molecular formula | C27H32N2O7S |
| CAS | 150591-06-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Katoh M, Karasawa T, Doi H, Odawara A. Effects of the antiplatelet agent TA-993 and its metabolite MB3 on the hemorheological properties of rat and human erythrocytes. Thromb Res. 2001 Oct 15;104(2):105-12. PubMed PMID: 11672754. 2. Katoh M, Karasawa T, Watanabe A, Takagi M, Ikeo T, Odawara A. Inhibitory effects of TA-993 and its metabolite MB3 on platelet activation induced by collagen and U-46619 in human platelets. Biol Pharm Bull. 2001 May;24(5):501-4. PubMed PMID: 11379769. 3. Doi H, Kaburaki M, Inoue H, Suzumura K, Narita H. Protective effect of TA-993, a novel therapeutic agent for peripheral circulatory insufficiency, on skeletal muscle fatigue in a rat model of hindlimb ischemia. Jpn J Pharmacol. 2000 May;83(1):73-81. PubMed PMID: 10887943. 4. Katoh M, Karasawa T, Doi H, Odawara A, Takagi M, Ikeo T, Narita H. Antiplatelet mechanisms of TA-993 and its metabolite MB3 in ADP-induced platelet aggregation. Eur J Pharmacol. 2000 Jul 7;399(2-3):91-6. PubMed PMID: 10884507. |