| Description | Sulfamethazine (Sulfadimidine) is a sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides. |
| In vivo | sulfamethazine 是一种对氨基苯甲酸的结构类似物和竞争性拮抗剂,可以抑制细菌利用氨基苯甲酸来合成叶酸,而叶酸是一种重要的DNA合成代谢物。Sulfamethazine还可以通过抑制二氢叶酸合成酶活性来抑制二氢叶酸合成。 |
| Synonyms | Sulfadimerazine, 磺胺二甲嘧啶, Sulfadimidine |
| molecular weight | 278.33 |
| Molecular formula | C12H14N4O2S |
| CAS | 57-68-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 50 mg/mL (179.64 mM) Ethanol: < 1 mg/mL (insoluble or slightly soluble) |
| References | 1. Perez S, et al. Environ Toxicol Chem, 2005, 24(6), 1361-1367. 2. Kaniou S, et al. Chemosphere, 2005, 60(3), 372-380. |