| Description | STS-E412 is a tissue-protective and selective EPOR/CD131 receptor activator for the study of neurological disorders. |
| Synonyms | STS E412, STSE412 |
| molecular weight | 318.76 |
| Molecular formula | C15H15ClN4O2 |
| CAS | 1609980-39-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 30 mg/mL (94.11 mM), Sonification is recommended. |
| References | 1. Miller JL, et al. Discovery and Characterization of Nonpeptidyl Agonists of the Tissue-Protective Erythropoietin Receptor. Mol Pharmacol. 2015 Aug;88(2):357-67. 2. Miller JL, Rai M, Frigon NL, Pandolfo M, Punnonen J, Spencer JR. Erythropoietin and small molecule agonists of the tissue-protective erythropoietin receptor increase FXN expression in neuronal cells in vitro and in Fxn-deficient KIKO mice in vivo. Neuropharmacology. 2017 Sep 1;123:34-45. doi: 10.1016/j.neuropharm.2017.05.011. Epub 2017 May 11. |