| Description | Steroid sulfatase-IN-1 is a highly potent and orally active inhibitor of the enzyme Steroid sulfatase, with an impressive IC50 value of 1.71 μM. This compound exhibits notable antitumor activity, achieving a TGI (tumor growth inhibition) of 51% in vivo. Therefore, Steroid sulfatase-IN-1 holds great promise in the field of breast cancer research [1]. |
| In vivo | Steroid sulfatase-IN-1 (compound 4 b) (50 mg/kg; p.o.) shows significant antitumor activity with the TGI value of 51% [1]. Animal Model: 67NR mouse [1] Dosage: 50 mg/kg Administration: P.o. Result: Showed significant antitumor activity with the TGI value of 51%. |
| molecular weight | 385.23 |
| Molecular formula | C14H10Cl2N4O3S |
| CAS | 2403716-19-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |