| Description | Squalamine is an aminosterol compound, with potent broad spectrum antiviral activity. |
| Synonyms | MSI-1256, 角鲨胺 |
| molecular weight | 627.96 |
| Molecular formula | C34H65N3O5S |
| CAS | 148717-90-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 100 mg/mL (159.25 mM), Sonication is recommended. |
| References | 1. Zasloff M, et al. Squalamine as a broad-spectrum systemic antiviral agent with therapeutic potential. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15978-83. 2. Hraiech S, et al. Antibacterial efficacy of inhaled squalamine in a rat model of chronic Pseudomonas aeruginosa pneumonia. J Antimicrob Chemother. 2012 Oct;67(10):2452-8. 3. Djouhri-Bouktab L, et al. Squalamine ointment for Staphylococcus aureus skin decolonization in a mouse model. J Antimicrob Chemother. 2011 Jun;66(6):1306-10. |