| Description | SQ-28429 is a synthetic monobactam. |
| Synonyms | Aztreonam E-isomer, SQ 28429 |
| molecular weight | 435.43 |
| Molecular formula | C13H17N5O8S2 |
| CAS | 99341-02-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Davido B, Dinh A, Senard O, Calin R, Makhloufi S, Salomon J. Repurposing an old drug: aztreonam as a new treatment strategy for gonorrhoea. J Antimicrob Chemother. 2017 May 1;72(5):1466-1468. doi: 10.1093/jac/dkw589. PubMed PMID: 28137938. 2. Bush K, Freudenberger JS, Sykes RB. Interaction of azthreonam and related monobactams with beta-lactamases from gram-negative bacteria. Antimicrob Agents Chemother. 1982 Sep;22(3):414-20. PubMed PMID: 6982680; PubMed Central PMCID: PMC183759. 3. Sykes RB, Bonner DP, Bush K, Georgopapadakou NH. Azthreonam (SQ 26,776), a synthetic monobactam specifically active against aerobic gram-negative bacteria. Antimicrob Agents Chemother. 1982 Jan;21(1):85-92. PubMed PMID: 6979307; PubMed Central PMCID: PMC181833. |