| Description | Spiroplatin (TNO-6) is a novel platinum-containing analogue with antitumor activity that is commonly used in the study of solid tumors. |
| molecular weight | 433.39 |
| Molecular formula | C8H18N2O4PtS |
| CAS | 74790-08-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Schroyens W, et al. Comparative effect of cisplatin, spiroplatin, carboplatin and iproplatin in a human tumor clonogenic assay. J Cancer Res Clin Oncol. 1990;116(4):392-6. 2. van der Vijgh WJ, et al. Pharmacokinetics of free and total platinum species after rapid and prolonged infusions of aqua (1,1-bis(aminomethyl)cyclohexane) sulfatoplatinum (II) (spiroplatin) during a phase I trial. Eur J Cancer Clin Oncol. 1988 Apr;24(4):621-7. |