| Description | Specific PXR antagonist 70 is a selective pregnane X receptor (PXR) antagonist with an IC50 of 540 nM and Ki of 390 nM for human PCR and enhances the chemosensitivity of cancer cells. |
| molecular weight | 415.51 |
| Molecular formula | C21H25N3O4S |
| CAS | 931314-31-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | H2O: 76.92 mg/mL (210 mM), Sonication is recommended. |
| References | 1. Chai SC, Lin W, Li Y, Chen T. Drug discovery technologies to identify and characterize modulators of the pregnane X receptor and the constitutive androstane receptor. Drug Discov Today. 2019 Mar;24(3):906-915. |