| Description | Sofosbuvir impurity G is both a diastereomer of Sofosbuvir and an impurity of Sofosbuvir which is an inhibitor of HCV RNA replication. |
| molecular weight | 529.45 |
| Molecular formula | C22H29FN3O9P |
| CAS | 1337482-15-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (94.44 mM) |
| References | 1. Baker MM, Hammad SF, Belal TS. Development and validation of a versatile HPLC-DAD method for simultaneous determination of the antiviral drugs daclatasvir, ledipasvir, sofosbuvir and ribavirin in presence of seven potential impurities. Application to assay of dosage forms and dissolution studies. Drug Dev Ind Pharm. 2019 Jul;45(7):1111-1119. |