| Description | Sodium 2-mercaptoethanesulfonate (Uromitexan) is a sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from antineoplastic agents, such as ifosfamide or cyclophosphamide. |
| Synonyms | Mitexan, 美司那, 美司钠, Uromitexan, Mesna, Mesnum, Mesnex |
| molecular weight | 164.18 |
| Molecular formula | C2H5NaO3S2 |
| CAS | 19767-45-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | Ethanol: < 1 mg/mL (insoluble or slightly soluble) DMSO: 55 mg/mL (335 mM), Sonication is recommended. H2O: 7 mg/mL (42.63 mM) |
| References | 1. Kalcioglu MT, et al. Am J Otolaryngol. 2014 May-Jun;35(3):357-61. |
| Citations | 1. Tang Y, Song H, Wang Z, et al. Repurposing antiparasitic antimonials to noncovalently rescue temperature-sensitive p53 mutations. Cell Reports. 2022, 39(2): 110622 2. Tang Y, Song H, Wang Z, et al.Repurposing antiparasitic antimonials to noncovalently rescue temperature-sensitive p53 mutations.Cell Reports.2022, 39(2): 110622. |
Sodium 2-mercaptoethanesulfonate
CAS No.: 19767-45-4
Sodium 2-mercaptoethanesulfonate (Uromitexan) is a sulfhydryl compound used to prevent urothelial toxicity by inactivati
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