| Description | SNIPER(ABL)-044, a compound that links HG-7-85-01 (ABL inhibitor) to Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels, achieving a DC50 value of 10 μM[1]. |
| molecular weight | 1020.17 |
| Molecular formula | C51H64F3N9O8S |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666. |