| Description | SNAP 398299, a galanin receptor antagonist, is a potential novel pharmacological treatment for mood disorders. |
| Synonyms | SNAP-398299, SNAP398299 |
| molecular weight | 479.49 |
| Molecular formula | C27H24F3N3O2 |
| CAS | 903878-06-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Scheller KJ, Williams SJ, Lawrence AJ, Jarrott B, Djouma E. An improved method to prepare an injectable microemulsion of the galanin-receptor 3 selective antagonist, SNAP 37889, using Kolliphor(®) HS 15. MethodsX. 2014 Sep 26;1:212-6. doi: 10.1016/j.mex.2014.09.003. eCollection 2014. PubMed PMID: 26150955; PubMed Central PMCID: PMC4472996. 2. Kothandan G, Gadhe CG, Cho SJ. Theoretical characterization of galanin receptor type 3 (Gal3 ) and its interaction with agonist (GALANIN) and antagonists (SNAP 37889 and SNAP 398299): an in silico analysis. Chem Biol Drug Des. 2013 Jun;81(6):757-74. doi: 10.1111/cbdd.12128. Epub 2013 Apr 17. PubMed PMID: 23461969. 3. Ogren SO, Kuteeva E, Hökfelt T, Kehr J. Galanin receptor antagonists : a potential novel pharmacological treatment for mood disorders. CNS Drugs. 2006;20(8):633-54. Review. PubMed PMID: 16863269. 4. Swanson CJ, Blackburn TP, Zhang X, Zheng K, Xu ZQ, Hökfelt T, Wolinsky TD, Konkel MJ, Chen H, Zhong H, Walker MW, Craig DA, Gerald CP, Branchek TA. Anxiolytic- and antidepressant-like profiles of the galanin-3 receptor (Gal3) antagonists SNAP 37889 and SNAP 398299. Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17489-94. Epub 2005 Nov 15. Erratum in: Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14978. Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5632. PubMed PMID: 16287967; PubMed Central PMCID: PMC1283534. |