| Description | SM19712 free acid is an inhibitor of nonpeptide endothelin converting enzyme. |
| Synonyms | SM 19712, SM-19712, SM19712 |
| molecular weight | 415.85 |
| Molecular formula | C18H14ClN5O3S |
| CAS | 194542-49-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Hasdemir B, Mahajan S, Bunnett NW, Liao M, Bhargava A. Endothelin-converting enzyme-1 actions determine differential trafficking and signaling of corticotropin-releasing factor receptor 1 at high agonist concentrations. Mol Endocrinol. 2012 Apr;26(4):681-95. doi: 10.1210/me.2011-1361. Epub 2012 Feb 9. PubMed PMID: 22322595; PubMed Central PMCID: PMC3327357. 2. Pelayo JC, Poole DP, Steinhoff M, Cottrell GS, Bunnett NW. Endothelin-converting enzyme-1 regulates trafficking and signalling of the neurokinin 1 receptor in endosomes of myenteric neurones. J Physiol. 2011 Nov 1;589(Pt 21):5213-30. doi: 10.1113/jphysiol.2011.214452. Epub 2011 Aug 30. PubMed PMID: 21878523; PubMed Central PMCID: PMC3225675. |