| Description | SKLB0565 is an effective inhibitor of tubulin. SKLB0565 significantly inhibited the proliferation of colorectal cancer cells with IC50 of 0.012 - 0.081 μ M。 SKLB0565 induces G2/M phase arrest and mitochondria-mediated endogenous apoptosis. SKLB0565 destroys the microtubule formation of HUVECs cells and inhibits cell migration. |
| molecular weight | 400.91 |
| Molecular formula | C20H25ClN6O |
| CAS | 2414607-10-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |