| Description | SJFδ is a 10-atom linker PROTAC. SJFδ degrades p38δ with a DC50 of 46.17 nM, but does not degrade p38α, p38β, or p38γ[1]. |
| Target activity | p38α:46.17 nM (DC50) |
| molecular weight | 1168.27 |
| Molecular formula | C62H63F2N7O12S |
| CAS | 2254609-23-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Smith BE, et al. Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase. Nat Commun. 2019 Jan 10;10(1):131. |