| Description | Simethicone (Disflatyl), an oral anti-foaming agent, can be used to reduce bloating, pain and discomfort caused by excess gas in the stomach or intestinal tract. |
| Synonyms | Disflatyl, 西甲硅油, Simeticone, Phazyme |
| molecular weight | N/A |
| Molecular formula | (C2H6OSi)n(SiO2)m |
| CAS | 8050-81-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: Soluble |
| References | 1. Barakat MT, Huang RJ, Banerjee S. Simethicone is retained in endoscopes despite reprocessing: impact of its use on working channel fluid retention and adenosine triphosphate bioluminescence values (with video). Gastrointest Endosc. 2018 Aug 17. pii: S0016-5107(18)32932-8. doi: 10.1016/j.gie.2018.08.012. [Epub ahead of print] PubMed PMID: 30125574. 2. Spinzi G, Andrealli A, Conforti FS. Use of N-acetylcysteine plus simethicone to improve mucosal visibility during upper GI endoscopy. Gastrointest Endosc. 2018 Sep;88(3):575. doi: 10.1016/j.gie.2018.04.2348. PubMed PMID: 30115313. 3. Kump P, Hassan C, Spada C, Brownstone E, Datz C, Haefner M, Renner F, Schoefl R, Schreiber F. Efficacy and safety of a new low-volume PEG with citrate and simethicone bowel preparation for colonoscopy (Clensia): a multicenter randomized observer-blind clinical trial vs. a low-volume PEG with ascorbic acid (PEG-ASC). Endosc Int Open. 2018 Aug;6(8):E907-E913. doi: 10.1055/a-0624-2266. Epub 2018 Aug 1. PubMed PMID: 30083580; PubMed Central PMCID: PMC6070370. 4. Pan P, Zhao SB, Li BH, Meng QQ, Yao J, Wang D, Li ZS, Bai Y. Effect of supplemental simethicone for bowel preparation on adenoma detection during colonoscopy: A meta-analysis of randomized controlled trials. J Gastroenterol Hepatol. 2018 Aug 1. doi: 10.1111/jgh.14401. [Epub ahead of print] PubMed PMID: 30069899. |