| Description | Showdomycin is an antibiotic with antineoplastic activity. |
| molecular weight | 229.19 |
| Molecular formula | C9H11NO6 |
| CAS | 16755-07-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Palmu K, Rosenqvist P, Thapa K, Ilina Y, Siitonen V, Baral B, Mäkinen J, Belogurov G, Virta P, Niemi J, Metsä-Ketelä M. Discovery of the Showdomycin Gene Cluster from Streptomyces showdoensis ATCC 15227 Yields Insight into the Biosynthetic Logic of C-Nucleoside Antibiotics. ACS Chem Biol. 2017 Apr 27. doi: 10.1021/acschembio.7b00078. [Epub ahead of print] PubMed PMID: 28418235. 2. De Clercq E. C-Nucleosides To Be Revisited. J Med Chem. 2016 Mar 24;59(6):2301-11. doi: 10.1021/acs.jmedchem.5b01157. Epub 2015 Oct 29. Review. PubMed PMID: 26513594. 3. Rudolf GC, Koch MF, Mandl FA, Sieber SA. Subclass-specific labeling of protein-reactive natural products with customized nucleophilic probes. Chemistry. 2015 Feb 23;21(9):3701-7. doi: 10.1002/chem.201405009. Epub 2015 Jan 21. PubMed PMID: 25605563. 4. Böttcher T, Sieber SA. Showdomycin as a versatile chemical tool for the detection of pathogenesis-associated enzymes in bacteria. J Am Chem Soc. 2010 May 26;132(20):6964-72. doi: 10.1021/ja909150y. PubMed PMID: 20433172. |