| Description | SHMT-IN-1 is a potent plasmodial serine hydroxymethyltransferase (SHMT) inhibitor with antitumor activity. |
| molecular weight | 375.25 |
| Molecular formula | C18H16Cl2N4O |
| CAS | 1508286-18-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 200 mg/mL (533 mM), Sonication is recommended. |
| References | 1. Witschel MC, et al. Inhibitors of plasmodial serine hydroxymethyltransferase (SHMT): cocrystal structures of pyrazolopyrans with potent blood- and liver-stage activities. J Med Chem. 2015 Apr 9;58(7):3117-30. |