Description | Sennidin B stimulates glucose incorporation in rat adipocytes. |
In vitro | The bacterium hydrolyzed sennosides A and Sennidin B to sennidin A and Sennidin B via sennidin A and Sennidin B 8-monoglucosides, respectively. Among nine species of Bifidobacterium having beta-glucosidase activity, only Bifidobacterium dentium and B. adolescentis metabolized sennoside B to Sennidin B, suggesting that the sennoside-metabolizing bacteria produce a novel type of beta-glucosidase capable of hydrolyzing sennosides to sennidins[1] |
molecular weight | 538.47 |
Molecular formula | C30H18O10 |
CAS | 517-44-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 10 mM |
References | 1. Isolation of a human intestinal anaerobe, Bifidobacterium sp. strain SEN, capable of hydrolyzing sennosides to sennidins.Appl Environ Microbiol. 1994 Mar;60(3):1041-3. |