| Description | Sekikaic acid is a phenolic lichen metabolite that has been found in H. obscurata and has diverse biological activities. It scavenges superoxide and DPPH radicals in cell-free assays when used at a concentration of 0.5 µM. Sekikaic acid is active against the rg recombinant strain of respiratory syncytial virus (RSV; IC50 = 5.69 µg/ml). It inhibits the protein-protein interaction between mixed lineage leukemia 1 (MLL1) and the GACKIX domain of CREB-binding protein (CBP; IC50 = 34 µM). |
| molecular weight | 418.44 |
| Molecular formula | C22H26O8 |
| CAS | 607-11-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |