| Description | SEC inhibitor KL-2 (KL-2) (KL-2) is a potent, selective super elongation complex (SEC) inhibitor. SEC inhibitor KL-2 exhibits a dose-dependent inhibitory effect on AFF4-CCNT1 interaction (Ki: 1.50 μM). |
| Synonyms | KL-2 |
| molecular weight | 333.74 |
| Molecular formula | C17H13ClFNO3 |
| CAS | 900308-51-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 75.0 mg/mL (224.7 mM), Sonication is recommended. |
| References | 1. Liang K, et al. Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced CancerTherapy. Cell. 2018 Oct 18;175(3):766-779. |