| Description | Sch 40853 is an active metabolite of a benzonaphthazepine antipsychotic agent. |
| Synonyms | Sch-40853, Sch40853 |
| molecular weight | 299.8 |
| Molecular formula | C18H18ClNO |
| CAS | 129672-23-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Lin CC, Kim HK, Parker D. Sensitive high-performance liquid chromatographic method for the determination of a benzonaphthazepine antipsychotic agent, SCH 39166, and its active metabolite, SCH 40853, in human plasma and its cross-validation with a gas chromatographic method. J Chromatogr B Biomed Appl. 1996 Jul 12;682(2):309-13. PubMed PMID: 8844424. 2. Tedford CE, Coffin VL, Ruperto V, Cohen M, McQuade RD, Johnson R, Kim HK, Lin CC. Determination of plasma and brain concentrations of SCH 39166 and their correlation to conditioned avoidance behavior in rats. Psychopharmacology (Berl). 1993;113(2):199-204. PubMed PMID: 7855181. 3. Halldin C, Farde L, Barnett A, Sedvall G. Synthesis of carbon-11 labelled SCH 39166, a new selective dopamine D-1 receptor ligand, and preliminary PET investigations. Int J Rad Appl Instrum A. 1991;42(5):451-5. PubMed PMID: 1646191. |